Brain death and the apnea test

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The Apnea Test and Rationale for Brain Death as Death*

I have been asked to address two subjects that are importantly related. One is a technical one on apnea, and because of this knowledgeable audience and the fact that it is essentially a technical issue, I am going to move through it fairly quickly. There are a few open questions in the apnea test, but they are essential to address. It is the last step in defining death and therefore requires th...

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Apnea test in the diagnosis of brain death.

BACKGROUND Brain death is the absence of all cortical functions, including the brainstem. The apnea test (AT) is a necessary requisite to complete this diagnosis. Anecdotal reports describing hypotension and acidosis due to apnea test have been reported. However, there are few studies that evaluate complications or difficulties related to this procedure. OBJECTIVE To analyze medical problems ...

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The apnea test for brain death determination: an alternative approach.

INTRODUCTION Problems associated with the standard apnea test relate to overshooting or undershooting the target PaCO2, potentially compromising the viability of organs for transplantation or invalidating the test. MATERIALS AND METHODS In 60 adult patients, the authors used an alternative method using exogenously administered CO2 and measurement of end-tidal CO2. RESULTS All patients achie...

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Apnea test in the determination of brain death in patients treated with extracorporeal membrane oxygenation (ECMO).

Extracorporeal Membrane Oxygenation (ECMO) is a well-established method of support in patients with severe respiratory and/or circulatory failure. Unfortunately, this invasive method of treatment is associated with a high risk of neurological complications including brain death. Proper diagnosis of brain death is crucial for the termination of futile medical care. Currently, the legal system in...

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Benefit of a single recruitment maneuver after an apnea test for the diagnosis of brain death

INTRODUCTION Many potential lung transplants are lost because of hypoxemia during donor management. We hypothesized that the apnea test, necessary to confirm the diagnosis of brain death in potential lung donors, was involved in the decrease in the ratio of partial pressure of arterial O₂ to fraction of inspired O₂ (PaO₂/FiO₂) and that a single recruitment maneuver performed just after the apne...

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ژورنال

عنوان ژورنال: Annals of Indian Academy of Neurology

سال: 2009

ISSN: 0972-2327

DOI: 10.4103/0972-2327.56327